Progression of hepatic neoplasia in medaka (Oryzias latipes) exposed to diethylnitrosamine
نویسندگان
چکیده
منابع مشابه
Cytotoxicity phase of diethylnitrosamine-induced hepatic neoplasia in medaka.
Adult Oryzias latipes were exposed to 50 mg of diethylnitrosamine per liter of water for 5 wk and then transferred to clean water for an additional 15 wk. Response of the liver during the first 6 wk were analyzed by enzyme histochemistry and by high-resolution light and transmission electron microscopy. After 1 wk, cytotoxicity was apparent at the light microscopic level by piecemeal necrosis a...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 1999
ISSN: 1460-2180
DOI: 10.1093/carcin/20.6.933